The chemopreventive effect of Ginkgo biloba and Silybum marianum extracts on hepatocarcinogenesis in rats

Table 2 Effect of silymarin and Ginkgo biloba extract on ALT, AST and GGT activities in the sera of rats of different experimental groups

*Groups*	*ALT(U/L)*	*AST(U/L)*	*GGT(U/L)*
*Control*	23.05 ± 1.68	62.47 ± 3.65	31.68 ± 4.38
*NDEA*	75.20 ± 1.52 ^a	101.22 ± 2.66 ^a	87.84 ± 10.45 ^a
*Pre S.m*	41.43 ± 1.13 ^b	82.27 ± 1.54 ^b	53.02 ± 4.77 ^b
*Pre G.b*	36.09 ± 1.24 ^b	81.62 ± 3.05 ^b	53.29 ± 7.68 ^b
*Post S.m*	53.55 ± 2.48 ^b,^c	92.23 ± 6.24 ^b,^c	68.03 ± 5.36 ^b,^c
*Post G.b*	46.97 ± 2.09 ^b,^d	95.47 ± 3.71 ^b,^d	68.27 ± 8.39 ^b,^d

Results are given as mean ± S.D. for 6 rats. Pre S.m= Pretreated silymarin, Pre G.b= Pretreated EGb, Post S.m= Posttreated silymarin, Post G.b= Posttreated EGb. a: significantly different from control group at p ≤ 0.05. b: significantly different from NDEA group at p ≤ 0.05. c: significantly different from Pre S.m group at p ≤ 0.05. d: significantly different from Pre G.b group at p ≤ 0.05.

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