Figure 4
From: Lycorine induces cell-cycle arrest in the G0/G1 phase in K562 cells via HDAC inhibition
Effects of lycorine on expression of cyclin D1, CDK4 and CDK2 in K562 cells. Tubulin was used for normalization and verification of protein loading in Western blot analysis. Lanes 1, 2, 3, and 4 represent K562 cells treated with 0, 1.25, 2.5, and 5.0 μM lycorine, respectively. Results are presented as mean ± S.D. (n = 3, three independent experiments). Asterisks (*) indicate significant difference (P < 0.05) compared with the control group.