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Figure 4 | Cancer Cell International

Figure 4

From: Restoration of klotho gene expression induces apoptosis and autophagy in gastric cancer cells: tumor suppressive role of klotho in gastric cancer

Figure 4

The role of demethylating agen and autophagy inhibitor on protein expression and phosphorylation. In GC-7901 cells, 5-Aza increased the level of klotho and decreased the levels of phospho-IGF-1R, phospho-PI3K, and phospho-mTOR, but had no effect on IGF-1R, PI3K, and mTOR levels. 3-MA significantly normalized the effect of 5-Aza.

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Cancer Cell International

ISSN: 1475-2867

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