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Figure 3 | Cancer Cell International

Figure 3

From: RNAi silencing of c-Myc inhibits cell migration, invasion, and proliferation in HepG2 human hepatocellular carcinoma cell line: c-Myc silencing in hepatocellular carcinoma cell

Figure 3

Invasion (a), motility (b) and proliferation (c) of parental, vector, and siRNAi-vector transfected cells. The percentages of invading (t=24 hours) and migrating (t=24 hours) cells were calculated as reported in Materials and Methods. The pictures highlighted the differences in number between HepG2, pS, and pS-c-Myc cells able to invade (a) or migrate (b) to the lower surface of transwells. RNAi directed against c-Myc led to a reduced cellular growth rate after 24, 48 and 72 hours. Columns, averages of three independent experiments; error bars, SD. *P <0.05.

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