Figure 1From: Blockade of PI3K/AKT pathway enhances sensitivity of Raji cells to chemotherapy through down-regulation of HSP70Effects of HT and LY294002 on expression of HSP70 and cell apoptosis. (A) Raji cells were cultured at 42.0°C for 1 hour and then they were returned to 37.0°C for the indicated time of recovery. The expression of HSP70 was detected by Western-Blot. (B) Apoptosis rate of Raji cells induced by LY294002 at indicated concentration was measured by FACS. (C) Raji cells were cultured at 42.0°C for 1 hour and then they were returned to 37.0°C for 8 hours or received LY294002 (20 μM) teratment for 8 hours. Expression of HSP70 and p-AKT in Raji cells were measured by Western-Blot.Back to article page