Figure 3

NMR proton spectra obtained at D3 on K562wt (left side) and K562adr (right side) on control cells (top spectra) or treated with 5 mM MCD during 2 hours (bottom spectra). Peak assignment – 1: CH3 from fatty acid chains; 2: CH2 from fatty acid chains; 3: Alanine; 4 : glutamine and glutamate; 5: creatine; 6 N-trimethyl from choline, 7: Inositol; 8 : CH₂ in β position from ester function in fatty acid ester; 9: CH2 in a position of a double bond in fatty acids; 10 : CH₂ in α position from ester function in fatty acid ester.