Table 12 Mutations of C to other bases in hypermutable codons 248 and 273
From: Mechanisms of genotoxin-induced transcription and hypermutation in p53
| Â | A | G | T |
|---|---|---|---|
Total C mutations including lung (728) | 11 | 21 | 696 |
Percent of total | 1.5% | 2.9% | 95.6% |
Lung mutations (63) | 3 | 2 | 58 |
Percent of lung | 4.8% | 3.2% | 92.1% |
Difference in total C mutations due to the presence of lung C mutations | +3.3% | +0.3% | -3.5% |