Figure 2

The UVA effect on the protein expression of cyclin G and on the cell cycle arrest in B16-F1 cells. The UVA effect on the protein expression of cyclin G in B16-F1 cell line is indicated by purple bars. The results are shown as the ratios, where the UVA treated value is divided by the control value. The cyclin G protein expression is moderately affected by UVA and there is a 1.36-fold increase in the cyclin G expression at 6-h time point. The UVA effect on the cell cycle arrest at the G2/M check point is indicated by black circles; non-exposed control cells are indicated by black triangles. The UVA exposure induces a significant cell cycle arrest, beginning at the 4-h time-point, peaking at the 8-h time-point in a statistically significant-manner (p < 0.05), and declining thereafter.