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Figure 3 | Cancer Cell International

Figure 3

From: BCYRN1, a c-MYC-activated long non-coding RNA, regulates cell metastasis of non-small-cell lung cancer

Figure 3

The change of BCYRN1 level in A549 cells (A), and migration and invasion of A549 cells (B ~ D; B: the quantitative results for figures C and D) after siRNA interference in c-MYC overexpressed cells. Blank control: the cells alone infected with pWPXL-c-Myc. pWPXL-c-Myc + siRNA-NC: the cells jointly treated with lentivirus (pWPXL-c-Myc) infection and siRNA transfection together. pWPXL-c-Myc + siRNA-BCYRN1-1 or −2: the cells jointly treated with lentivirus (pWPXL-c-Myc) infection and siRNA transfection (the two specific siRNAs of BCYRN1were respectively named as siRNA-BCYRN1-1 and siRNA-BCYRN1-2). Magnification: 100 ×. ** p < 0.01, indicated a very significant difference, compared with control.

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Cancer Cell International

ISSN: 1475-2867

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