Figure 1

Microarray data analysis. a The result from Hierarchical Clustering showed part of the distinguishable lncRNA expression profiles among 3 paired LAC and adjacent normal tissues. “Red” indicates high relative expression; and “green” indicates low relative expression. b The scatter-plot was used for assessing the lncRNA expression variation among 3 paired LAC and adjacent normal tissues. The values of x-axis and y-axis in the scatter-plot were the normalized signal values of each sample (log 2 scaled). The green lines are fold change lines (the default fold change value given is 2.0). The lncRNAs above the top green line and below the bottom green line indicated > 2.0-fold change in expression of lncRNAs among the 3 compared samples. “Red” denotes high relative expression levels, and “blue” denotes low relative expression levels. c KEGG pathway analysis revealed that lncRNA DLX6-AS1was involved in cell proliferation process with JAK/STAT signaling pathway. The yellow squares represent key elements in cell proliferation progression.