Fig. 2

The TMZ-treated T98GTMZ have an increased CIN. a The karyotype differences between cell lines were demonstrated by alignment and comparison of karyographs of vehicle- and TMZ-treated derivatives. A list of all CCAs/NCCAs (in the same order as depicted on the x-axis of karyographs) and their copy number variation can be found in Additional file 3: Table S3. b A summary of karyotypic parameters of each cell line. c Chromosomal ideograms showing the areas of genetic gain/loss. Bars on the left (red colour) represent areas of copy number loss, whereas bars on the right (green colour) represent areas of copy number gain. Arrows depict the most obvious copy number alteration (CNA) differences between cell lines. Detailed description of copy number alterations (CNAs) can be found in Additional file 4: Table S4