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Fig. 2 | Cancer Cell International

Fig. 2

From: Induction of apoptosis and proliferation inhibition of hepatocellular carcinoma by 6-chloro-2-methoxy-N-(phenylmethyl)-9-acridinamine (BA): in vitro and vivo studies

Fig. 2

Effect of BA on SMMC-7721 cell migration and apoptosis. a, b SMMC-7721 cells treated with various concentrations of BA (0, 2, 4 and 8 μM) for 24 h. a Representative images of SMMC-7221 cells number in the transwell chamber membrane after BA treated. b Hematoxylin & eosin staining showing the morphological changes of SMMC-7721 cells after BA treatment. c Quantification of the migration of SMMC-7721 cells; data here represents replicates of three independent experiments and is expressed as the means ± standard deviation. d Apoptosis rate of SMMC-7221 cells induced by increasing concentrations of BA. Data here represents replicates of three independent experiments, and is expressed as the mean ± standard deviation. Data was analyzed using the Student’s t test. e Annexin V-FITC/Propidium iodide (PI) staining showing the apoptosis rate of SMMC-7721 cells after BA treatment (0, 2, 4, 8, 16 μM) for 24 h. *p < 0.05, compared to the control group

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Cancer Cell International

ISSN: 1475-2867

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