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Fig. 5 | Cancer Cell International

Fig. 5

From: Induction of apoptosis and proliferation inhibition of hepatocellular carcinoma by 6-chloro-2-methoxy-N-(phenylmethyl)-9-acridinamine (BA): in vitro and vivo studies

Fig. 5

Mechanistic studies of BA anti-hepatocellular carcinoma effect. a PI3K p85ɑ, P-Akt and Akt expression in SMMC-7721 cells treated with increasing concentrations of BA (0, 2, 4, 8, 16 μM) for 24 h. b The change of PI3K p85α, P-Akt and Akt expression in BA treated SMMC-7721 cells over time. SMMC-7721 cells were treated with 8 μM BA, and their PI3K p85α, P-Akt and Akt expression were measured at 0, 12, 24, 36, 48, 72 h after the treatment. β-actin was used as a loading control

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