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Fig. 7 | Cancer Cell International

Fig. 7

From: Induction of apoptosis and proliferation inhibition of hepatocellular carcinoma by 6-chloro-2-methoxy-N-(phenylmethyl)-9-acridinamine (BA): in vitro and vivo studies

Fig. 7

The effect of BA on body weight, liver, kidney, spleen and lung functions of mice. Nude mice bearing hepatocellular carcinoma tumor xenografts were treated with DMSO/normal saline (as the non-treated control), 5-FU (10 mg/kg) or BA (5, 10 mg/kg) separately once a day for 5 days. Their body weight, liver, kidney, spleen and lung functions were measured at the day 20. a Changes in body weight of nude mice. Asterisk from the first day the body weight of mice was significantly different compared with the control group. b The hematoxylin and eosin staining of the liver, kidney, spleen and lungs. *p < 0.05, vs control

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