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Table 1 The effect of BA on the liver and kidney function of mice

From: Induction of apoptosis and proliferation inhibition of hepatocellular carcinoma by 6-chloro-2-methoxy-N-(phenylmethyl)-9-acridinamine (BA): in vitro and vivo studies

Group

ALT (U/L)

A/G

TBIL (μmol/L)

AST (U/L)

BUN (mmol/L)

CR (μmol/L)

Control

71.0 ± 18.2

1.70 ± 0.23

1.94 ± 0.67

266 ± 70.11

8.43 ± 1.20

13.60 ± 6.47

BA (5 mg/kg)

73.8 ± 39.4

1.46 ± 0.25

0.94 ± 1.61

174 ± 118

8.67 ± 3.77

4.00 ± 2.00

BA (10 mg/kg)

92.2 ± 13.6

1.65 ± 0.17

1.70 ± 0.97

356 ± 92.6

9.85 ± 1.86

13.40 ± 7.02

5-Fu (10 mg/kg)

98.0 ± 34.7

1.40 ± 0.10

0.20 ± 0.00*

549 ± 361

15.1 ± 8.06

8.33 ± 5.77

  1. ALT alanine aminotransferase, A/G the proportion of albumin and globulins, TBIL total bilirubin, AST aspartate aminotransferase, BUN blood urea nitrogen, CR creatinine
  2. * p < 0.05, compared to control group