Table 1 The signal pathways to regulate the biological behaviors of PSCs
From: Chemotherapy and tumor microenvironment of pancreatic cancer
| Â | Proliferation | Migration | ECM production |
|---|---|---|---|
Hedgehog | Â | + | Â |
JAK-STAT | + | Â | Â |
MAPK | + | + | + |
PI3K | + | + | + |
PKC | Â | Â | + |
Rho kinase | Â | Â | + |
Smads | Â | Â | + |
Wnt/β-catenin | + |  | + |
PPAPγ | + |  |  |
TF(AP-1, NK-κB, Gli-1) | + | + | + |