EP300 single nucleotide polymorphism rs20551 correlates with prolonged overall survival in diffuse large B cell lymphoma patients treated with R-CHOP

Table 1 DLBCL patients’ characteristics and their correlations with the genotype of EP300 SNP rs20551

Clinical parameters	No.	Genotype		p	Clinical parameters	No.	Genotype		p
Clinical parameters	No.	AA	GA	p	Clinical parameters	No.	AA	GA	p
Gender					Stage
Male	108	91	17	0.779	I–II	97	85	12	0.330
Female	118	101	17		III–IV	129	107	22
Age					IPI score
≤60	144	123	21	0.797	0–2	151	128	23	0.911
>60	82	69	13		3–5	75	64	11
B symptoms					Ki67
Positive	147	126	21	0.663	≤75%	101	90	11	0.158
Negative	79	66	13		>75%	113	93	20
LDH					Subtype
Positive	107	94	13	0.248	GCB	54	46	8	0.969
Negative	119	98	21		non-GCB	153	130	23
β2-MG					Extra nodal site
Positive	56	46	10	0.385	≤1	159	133	26	0.420
Negative	160	139	21		>1	66	58	8
ESR					HBV infection
Positive	133	115	18	0.936	Positive	110	93	17	0.764
Negative	79	68	11		Negative	114	98	16
ECOG
0–1	208	178	30	0.313
2–3	17	13	4

LDH lactate dehydrogenase, MG microglobulin, ESR erythrocyte sedimentation rate, ECOG Eastern Cooperative Oncology Group, IPI International Prognostic Index, GCB germinal center B cell subtype, HBV hepatitis-B virus

ISSN: 1475-2867