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Table 3 Clinical response to R-CHOP therapy according to the genotype of EP300 SNP rs20551

From: EP300 single nucleotide polymorphism rs20551 correlates with prolonged overall survival in diffuse large B cell lymphoma patients treated with R-CHOP

Response

Genotype

p

AA

GA

All patients

 CR

130

22

0.731

 PR + PD + SD

62

12

 

 OR

163

31

0.333

 PD + SD

29

3

 

Non-GCB subtype

 CR

84

12

0.255

 PR + PD + SD

46

11

 

 OR

110

21

0.399

 PD + SD

20

2

 

GCB subtype

 CR

36

8

0.144

 PR + PD + SD

10

0

 

 OR

39

8

0.237

 PD + SD

7

0

 
  1. CR complete response, PR partial response, OR overall response, SD stable disease, PD progressive disease
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Cancer Cell International

ISSN: 1475-2867

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