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Fig. 5 | Cancer Cell International

Fig. 5

From: Mechanism study of oleanolic acid derivative, K73-03, inducing cell apoptosis in hepatocellular carcinoma

Fig. 5

Induction of the p65 transduction in nuclear autophagy and apoptosis by K73-03 in HepG2 cells through activating JAK2/STAT3 signal pathways. (A) The expressions of COX-2, p65 in nuclear and p-p65 in cytoplasm in HepG2 cells were analyzed by Western blotting. (B) After treatment with K73-03, the subcellular localization of p65 was examined by immunofluorescence staining with inverted fluorescence microscope. (C) The expressions of JAK/p-JAK, STAT/p-STAT in HepG2 cells were analyzed by Western blotting. The data were presented as the mean ± SD of three independent experiments. (*p < 0.05, **p < 0.01, significantly different from control group)

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