Fig. 2

Relative miRNA expression in normal and tumor cell samples. A Eight differentially expressed miRNAs (miR-1-3p, miR-129-5p, miR-141-3p, miR-146b-5p, miR-187-3p, miR-200a-3p, miR-200b-5p, and miR-486-5p) were identified in KIRC and NC serum samples (n = 28 each). B Five differentially expressed miRNAs (miR-1-3p, miR-129-5p, miR-187-3p, miR-146b-5p, and miR-200a- 3p) were identified in KIRC and NC serum samples (n = 84 each). The p values of ROC curves for miR-1-3p, miR-129-5p, miR-146b-5p, miR-187-3p, and miR-200a-3p were all were < 0.05 and the corresponding area under the curve values were 0.642, 0.618, 0.681, 0.712, and 0.612, respectively.* indicates p < 0.05, ** indicates p < 0.01, ***indicates p < 0.001