Fig. 3

ROC curve evaluation of the three-miRNA panel. This three-miRNA panel contained miR-1-3p, miR-129-5p, and miR-146b-5p, and the AUC for the panel was 0.895 (95% CI: 0.848 to 0.942; sensitivity = 89.30%, specificity = 76.19%). The diagnostic efficacy was evaluated as follows: AUC 0.5–0.7 (low), 0.7–0.9 (medium), and 0.9–1.0 (high)