Fig. 6

Correlations of the DRG score with immunotherapy and chemotherapeutic sensitivity in HCC. A Compared to patients in TCGA-LIHC with low DRG scores, those in the high DRG score group exhibited higher TIDE scores (Wilcoxon, P < 0.01). B The response rate of the high DRG score group was significantly lower than that of the low DRG score group (chi sq. test P < 0.001). C Correlations of the DRG scores and drug sensitivity in patients (Spearman correlation < − 0.2). The therapeutic sensitivity of cisplatin D, vinorelbine E, sorafenib F, and gefitinib G between the high- and low-risk groups. DRGs Disulfidptosis-related genes, TIDE Tumor immune dysfunction and exclusion