Fig. 1From: AAA237, an SKP2 inhibitor, suppresses glioblastoma by inducing BNIP3-dependent autophagy through the mTOR pathwayAAA237 suppressed viability and inhibited the proliferation of GBM cells in a dose- and time-dependent manner. A After incubation with different concentrations (0, 0.1, 1 and 3 μM) of AAA237 for 48 h, the changes in cell morphology were imaged. Scale bar = 100 μm. IC50 of AAA237 on U251 (B) and LN229 cells (C) at 48 and 72 h. CCK8 assay shows that AAA237 inhibits proliferation of U251 (D) and LN229 (E) cellsBack to article page