Fig. 3From: ATP1A1 is a promising new target for melanoma treatment and can be inhibited by its physiological ligand bufalin to restore targeted therapy efficacyConfocal microscopy of ATP1A1 in melanoma cells. A, B. Immunofluorescence images of ATP1A1 (red) and Cav1 (green) in HBL cells (nucleus in blue); a colocalisation of ATP1A1 and Cav-1 is observed in 2D (A) and 3D (B) images. C The colocalization was confirmed by PLA; the green spots indicate a physical interaction between the two proteins, nuclei are stained in blue with DAPI whereas phalloidin was used to stain cell cytoplasm in red. Scale bars = 5 µm)Back to article page