From: Abnormal arginine synthesis confers worse prognosis in patients with middle third gastric cancer
Parameter | Univariate survival analysis | Multivariate survival analysis | |||||
---|---|---|---|---|---|---|---|
HR | 95%CI | p | HR | 95%CI | p | ||
Age at diagnosis | |||||||
< 60 | 1.000 | ||||||
≥ 60 | 1.628 | 0.878–3.021 | 0.122 | ||||
Gender | |||||||
Male | 1.000 | ||||||
Female | 1.116 | 0.571–2.181 | 0.748 | ||||
Tumor size (cm) | |||||||
< 5 | 1.000 | ||||||
≥ 5 | 1.298 | 0.706–2.387 | 0.748 | ||||
Histologic type | |||||||
Adenocarcinoma | 1.000 | ||||||
Signet ring cell carcinoma | 1.441 | 0.348–5.969 | 0.614 | ||||
Degree of differentiation | |||||||
Medium-low/Medium/High | 1.000 | ||||||
Low | 1.167 | 0.637–2.140 | 0.617 | ||||
Location | |||||||
Other locations | 1.000 | ||||||
Middle third | 2.179 | 1.109–4.281 | 0.024 | 2.723 | 1.334–5.520 | 0.005 | |
Depth of invasion | |||||||
T1/T2 | 1.000 | ||||||
T3/T4 | 3.705 | 1.142–12.017 | 0.029 | 3.357 | 1.007–11.186 | 0.049 | |
Lymph node status | |||||||
N0/N1/N2 | 1.000 | ||||||
N3 | 5.676 | 2.953–10.910 | < 0.001 | 5.287 | 2.723–10.265 | < 0.001 | |
Distant metastasis | |||||||
M0 | 1.000 | ||||||
M1 | 3.305 | 1.001–10.914 | 0.049 | ||||
TNM stage | |||||||
Stage I/II | 1.000 | ||||||
Stage III/IV | 4.214 | 1.651–10.751 | 0.003 |