Fig. 6

The modified GZT treatment inhibits tumor growth in vivo by regulating intestinal flora. A Schematic diagram of fecal gavage experiment in BALB/c mice. B Photographs of tumors in mice. C Tumor volume growth curve. D Tumor weight change curve. E Histopathological changes observed by HE staining (200 × , scale bar: 100 μm); F The expression level of GSDMD was assessed by IHC (magnification: 200 × , scale bar: 50 μm). G Ki67 immunohistochemical staining was used to detect cell proliferation (200 × , scale bar: 100 μm). H Western blot was used to detect the protein expression levels of CD147, VEGF and MMP-9 in the Model (FMT) and the Higher Dose (FMT) group. ^*P < 0.05; ^**P < 0.01 vs. Model group