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Fig. 4 | Cancer Cell International

Fig. 4

From: What role does GPR65 play in the progression of osteosarcoma? Its mechanism and clinical significance

Fig. 4

The expression pattern of GPR65 in OS microenvironment. (A) Distribution map of different cell Subclusters in OS Microenvironment from single-cell sequencing data. (B) GPR65 was mainly expressed on CD4 + T cells (cluster 6), CD8 + T cells (cluster 0), OS associated macrophage cells (cluster 2). (C&G) FGFR1 and CDH11 is mainly expressed on Osteoclast or OS cells (cluster 8). (D) CD 8A was mainly expressed on OS associated CD8 + T cells (cluster 0). (E) CD4 was mainly expressed on OS associated CD4 + T cells (cluster 6). (F) CD68 was mainly expressed on OS associated macrophage cells (cluster 2). (H) CD14 was mainly expressed on OS associated macrophage cells or monocytes (cluster 2). (I) PPIB was expressed in all cell clusters 0–8, especially in the cell cluster 0–3. The expression of above gene in different cells from GEO database (GSE162454)

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Cancer Cell International

ISSN: 1475-2867

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