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Fig. 3 | Cancer Cell International

Fig. 3

From: Single-cell N6-methyladenosine-related genes function within the tumor microenvironment to affect the prognosis and treatment sensitivity in patients with gastric cancer

Fig. 3

M6A-related mRNA modification modifies the features of fibroblasts. (A) t-SNE plot of 11 fibroblast subclusters in the TME. (B) t-SNE plot of 4 fibroblast subtypes in the TME. (C) t-SNE plot of MRG score in 4 fibroblast subtypes. (D) Marker genes of each fibroblast subtype. (E) Expression level of marker genes in 4 fibroblast subtypes. F-H. Differentiation trajectory of fibroblasts, colored for cell types (F), states (G), and pseudotime (H). I. Heatmap of dynamic changes of 114 SCMRGs with pseudotime. J. The number of interactions among different TME cell subtypes. K. The strength of interactions among different TME cell subtypes. L. Receptor-ligand pairs that regulate fibroblasts. M. Receptor-ligand pairs regulated by fibroblasts

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