Table 2 Abnormal expression of SLC16A1-AS1 and its clinical significance in different cancers
From: Biological roles of SLC16A1-AS1 lncRNA and its clinical impacts in tumors
Tumor type | Expression | Clinical features | Prognosis | Diagnosis | Ref. |
|---|---|---|---|---|---|
Glioblastoma | Upregulated in cancer tissues | Tumor size | / | / | [93] |
Upregulated in cancer tissues | Clinical stage, KPS score | OS | / | [94] | |
Oral squamous cell carcinoma | Downregulated in cancer tissues | Tumor size | / | / | [95] |
Upregulated in cancer tissues | Histologic grade | OS | / | [96] | |
Hepatocellular carcinoma | Upregulated in cancer tissues | / | OS | / | [97] |
Downregulated in cancer tissues | / | OS | / | [98] | |
Upregulated in cancer tissues | / | OS, PFS, and DmFS | AUC (OS):0.785, AUC(PFS): 0.808, AUC(DmFS): 0.764 | [100] | |
Upregulated in cancer tissues | / | OS | / | [99] | |
Pancreatic ductal adenocarcinoma | Upregulated in PDAC stroma than in the epithelium | / | / | / | [138] |
Colorectal cancer | Upregulated in cancer tissues | BRAF mutation | / | AUC: 0.668 | [139] |
Upregulated in cancer tissues | / | OS | AUC: 0.88 | [140] | |
Renal cell carcinoma | Upregulated in cancer tissues | / | / | / | [145] |
Upregulated in cancer tissues | / | OS | / | [101] | |
Upregulated in cancer tissues | / | / | AUC: 0.6022 | [146] | |
Upregulated in cancer tissues | / | OS | / | [141] | |
Bladder cancer | Upregulated in high grade tumor tissues | / | / | AUC: 0.923 | [102] |
Upregulated in cancer tissues | / | / | / | [147] | |
Endometrial carcinoma | Upregulated in cancer tissues | Clinical stage, histological grade | OS | / | [143] |
Cervical squamous cell carcinoma | Downregulated in cancer tissues | / | OS | / | [103] |
Breast cancer | Upregulated in cancer tissues | / | / | / | [104] |
Downregulated in cancer tissues | Tumor size, TNM, LNM | OS, DFS | / | [105] | |
Downregulated in cancer tissues | / | / | / | [106] | |
Downregulated in plasma of breast cancer | / | / | / | [142] | |
Osteosarcoma | Upregulated in cancer tissues | / | / | / | [107] |
Non-small cell lung cancer | Downregulated in cancer tissues | Sex, smoking, vital status | OS, PFS | / | [108] |