Fig. 6
From: circ-TFRC downregulation suppresses ovarian cancer progression via miR-615-3p/IGF2 axis regulation
Overexpression of IGF2 or inhibition of miR-615-3p reversed OC cell proliferation and migration after circ-TFRC silencing. (A–C) EdU detection showed the proliferation ability of both SKOV3 and A2780 cells. The data are expressed as the mean ± SD. ***P < 0.001 versus NC. ###P < 0.001 versus sh-circ-TFRC. n = 3. (D–F) Transwell assay showed the invasion and migration of SKOV3 and A2780 cells. The data are expressed as the mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001 versus NC. ##P < 0.01, ###P < 0.001 versus sh-circ-TFRC. n = 3