Fig. 7From: The troglitazone derivative EP13 disrupts energy metabolism through respiratory chain complex I inhibition in breast cancer cells and potentiates the antiproliferative effect of glycolysis inhibitorsEP13 does not affect ATP levels in MDA-MB-231 and MCF-7 cells. MDA-MB-231 (a, b) and MCF-7 (c, d) cells were treated with vehicle or EP13 (6 μM) for 4 and 24 h. Intracellular ATP levels were measured using the CellTiter-Glo® kit and normalized relative to cell numbers. The results are depicted as the mean ± SEM of at least three independent measurements. Significant differences from control cells are indicated (*, p < 0.5)Back to article page