Table 3 Functional annotation of the six significant variants in the PSCA gene on chromosome 8q24
From: Significance of PSCA as a novel prognostic marker and therapeutic target for cancer
Variant | Annotation | Position | Clonal heterogeneity | ||
|---|---|---|---|---|---|
None | Moderate | High | |||
rs2294008 | Missense | 143761931 | Duodenal ulcer and gastric ulcer | – | Gastric cancer |
– | Gastritis | – | |||
rs138377917 | Stop-gain | 143763531 | – | – | Gastric cancer |
rs2976392 | Intergenic | 143762932 | – | – | Gastric cancer |
rs9297976 | Intergenic | 143752235 | Gatric cancer | – | – |
rs2976391 | Intergenic | 143762724 | – | Gastric cancer | – |
rs12155758 | Intergenic | 143765885 | Bladder cancer | – | – |