Skip to main content
Fig. 2 | Cancer Cell International

Fig. 2

From: Sparassis latifolia and exercise training as complementary medicine mitigated the 5-fluorouracil potent side effects in mice with colorectal cancer: bioinformatics approaches, novel monitoring pathological metrics, screening signatures, and innovative management tactic

Fig. 2

Data set analysis and enrichment assessment. A The visualization of significant DEG in colorectal cancer based on the microarray dataset is depicted in the heatmap diagram, with consideration of a P-value < 0.001. B The genetic network of 97 hub genes in colorectal cancer development and progression (GSE110224) was presented based on network diameters (Degree = 5, betweenness centrality = 0.006, and closeness centrality = 0.2). C The verification of hub gene's function in biological systems confirmed their involvement in a range of processes, including adenoma/adenocarcinoma, malignancy, metastasis, extracellular structure organization, PI3K-Akt signaling pathway, IL-4/IL-13/IL-17/IL-18, inflammation and inflammatory response pathway, matrix metalloproteinases, and AGE-RAGE signaling pathway

Back to article page

Cancer Cell International

ISSN: 1475-2867

Contact us