Effect of 5-azacytidine and galectin-1 on growth and differentiation of the human b lymphoma cell line bl36

Table 1 Modulation of urface Markers on BL36 Cells by AzaC

Surface marker	Control	Treatment AzaC = 5 μM	AzaC- 10 μM	AzaC = 50 μM
CD 19	94.9	88.5	86.1	58.1
CD 21	<20	<20	<20	20.3
CD 23	31.5	47.6	45.2	63.8
CD 30	<20	<20	48.4	21.5
CD 45 RA	76.7	74.4	71.2	64.6
CD 45 RO	21.4	35.1	33.3	38.5
CD 71	97.3	94.9	93.8	83.8
CD 138	<20	23.9	23.8	24.8

BL36 cells were exposed with 5 μM, 10 μM and 50 μM AzaC for 4 days. Then cell surface antigens were analyzed by flow cytometry. Values below 20% were considered as negative. In the same conditions, CDs 3 and 10 remain negative, and no variability was observed for CDs 11 a, 18, 25, 38, 44, 48, 54, 58, 77, 80, and 95.

ISSN: 1475-2867