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  1. Circular RNAs (circRNAs) which are shown as a class of RNAs exhibit the importance in the regulation of gene expression and the development of biological process. However, the expression profile and molecular ...

    Authors: Zhen Zhang, Honglei Wu, Zhaosheng Chen, Guangchun Li and Bin Liu

    Citation: Cancer Cell International 2020 20:25

    Content type: Primary research

    Published on:

  2. Increasing evidences have underlined the importance of long non-coding RNAs (lncRNAs) in human malignancies. LINC00958 has been found involved in some cancers. However, the underlying mechanical performance of...

    Authors: Longhai Yang, Lili Li, Zizi Zhou, Yi Liu, Jinyuan Sun, Xiaoming Zhang, Huiyu Pan and Song Liu

    Citation: Cancer Cell International 2020 20:24

    Content type: Primary research

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  3. Retinoblastoma (RB) is acknowledged to be the commonest intraocular malignancy in infants and children and the outcome of RB patients is unfavorable due to limited early diagnosis and effective therapy. SMAD f...

    Authors: Hui Wang and Xiang Ji

    Citation: Cancer Cell International 2020 20:23

    Content type: Primary research

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  4. Immune-related genes (IRGs) were linked to the prognosis of head and neck squamous cell carcinoma (HNSCC). This study aimed to identify the effects of an immune-related gene signature (IRGS) that can predict t...

    Authors: Yangyang She, Xiangbo Kong, Yaping Ge, Ping Yin, Zhiyong Liu, Jieyu Chen, Feng Gao and Silian Fang

    Citation: Cancer Cell International 2020 20:22

    Content type: Primary research

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  5. After publication of our article [1] it was highlighted by the authors that the type of this article was primary research, instead of review.

    Authors: Shengnan Zhang, Mengjuan Li, Fangfang Yuan, Lin Chen, Ruihua Mi, Xudong Wei, Yongping Song and Qingsong Yin

    Citation: Cancer Cell International 2020 20:21

    Content type: Correction

    Published on:

    The original article was published in Cancer Cell International 2019 19:272

  6. The erythropoietin-producing hepatocellular (Eph) receptor A5 (EphA5) has been found to be overexpressed in some malignant tumors and is associated with disease prognosis. However, the role of EphA5 in esophag...

    Authors: Rui Zhang, Jing Liu, Wei Zhang, Lei Hua, Li-Ting Qian and Shao-Bing Zhou

    Citation: Cancer Cell International 2020 20:20

    Content type: Primary research

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  7. Preeclampsia (PE) is a prevalent pregnancy disorder that has been one of the leading causes of maternal and perinatal mortality worldwide. Circular RNAs (circRNAs) have recently considered as important regulat...

    Authors: Bing Zhou, Xia Zhang, Ting Li, Rongping Xie, Jianbin Zhou, Yu Luo and Chunfen Yang

    Citation: Cancer Cell International 2020 20:19

    Content type: Primary research

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  8. There are different treatments for breast cancer and melanoma that mostly have some side effects. One of the therapeutic strategies is the use of natural components. Phenol components are a class of antioxidan...

    Authors: Khatereh Khorsandi, Zahra Kianmehr, Zohreh hosseinmardi and Reza Hosseinzadeh

    Citation: Cancer Cell International 2020 20:18

    Content type: Primary research

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  9. Microtubule-associated proteins 7(MAP7) was reported to be engaged into the function of neuronal function. The function of MAP7 in human cervical cancer (CC) was unknown. We aimed to uncover the function and m...

    Authors: Li Zhang, Xudong Liu, Lina Song, Hui Zhai and Chaohua Chang

    Citation: Cancer Cell International 2020 20:17

    Content type: Primary research

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  10. To evaluate the prognostic value of pretreatment lymphocyte counts with respect to clinical outcomes in patients with solid tumors.

    Authors: Jiawen Zhao, Weijia Huang, Yongxian Wu, Yihuan Luo, Bo Wu, Jiwen Cheng, Junqiang Chen, Deyun Liu and Chengyang Li

    Citation: Cancer Cell International 2020 20:15

    Content type: Primary research

    Published on:

  11. Increasing evidence has suggested that microRNAs (miRNAs) act as key post-transcriptional regulators in tumor progression. Previous studies have confirmed that miR-17-5p functions as an oncogene in multiple ca...

    Authors: Jian-Xing Wang, Xin-Ju Jia, Yan Liu, Jin-Hui Dong, Xiu-Min Ren, Ou Xu, Sheng-Hui Liu and Chun-Guang Shan

    Citation: Cancer Cell International 2020 20:14

    Content type: Primary research

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  12. microRNA Let-7 serves as a tumor suppressor by targeting various oncogenic pathways in cancer cells. However, the underlying mechanism of its involvement in breast cancer remains largely unknown. With our rese...

    Authors: Hongbin Wang, Yanlv Ren, Cheng Qian, Jiaxin Liu, Ge Li and Zhigao Li

    Citation: Cancer Cell International 2020 20:13

    Content type: Primary research

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  13. Melanoma is the most aggressive type of skin cancer with high mortality rate and poor prognosis. lncRNA MEG3, a tumor suppressor, is closely related to the development of various cancers. However, the role of ...

    Authors: Liangcai Wu, Lifei Zhu, Yanchang Li, Zhixin Zheng, Xi Lin and Chaoying Yang

    Citation: Cancer Cell International 2020 20:12

    Content type: Primary research

    Published on:

  14. Rapid progression contributes to treatment failure in anaplastic thyroid carcinoma (ATC) patients. In a preliminary study, we demonstrated that some hematopoietic factors may be involved in the progression of ...

    Authors: Zhao-Ming Zhong, Xue Chen, Xiao Qi, Xue-Min Wang, Chun-Yan Li, Ru-Jia Qin, Shi-Qi Wang, Jin Liang, Mu-Sheng Zeng and Chuan-Zheng Sun

    Citation: Cancer Cell International 2020 20:11

    Content type: Primary research

    Published on:

  15. Accumulating evidence has associated aberrant long non-coding RNAs (lncRNAs) with various human cancers. This study aimed to explore the role of LINC00908 in prostate cancer (PCa) and its possible underlying m...

    Authors: Li Fan, Hai Li and Yun Zhang

    Citation: Cancer Cell International 2020 20:10

    Content type: Primary research

    Published on:

  16. Aurora kinase A (AURKA) has been implicated in the regulation of cell cycle progression, mitosis and a key number of oncogenic signaling pathways in various malignancies including neuroblastoma. Small molecule...

    Authors: Yan Yang, Lili Ding, Qi Zhou, Li Fen, Yuhua Cao, Junjie Sun, Xuefeng Zhou and Aiguo Liu

    Citation: Cancer Cell International 2020 20:9

    Content type: Primary research

    Published on:

  17. Accumulating evidence indicates that the long noncoding RNA taurine upregulated gene 1(TUG1) plays a critical role in cancer progression and metastasis. However, the overall biological role and clinical signif...

    Authors: Qun Dai, Jingyi Deng, Jinrong Zhou, Zhuhong Wang, Xiao-feng Yuan, Shunwen Pan and Hong-bin Zhang

    Citation: Cancer Cell International 2020 20:8

    Content type: Primary research

    Published on:

  18. CTLA-4 is a well-studied immune checkpoint protein that negatively regulates T cell-mediated immune responses. However, the expression of CTLA-4 in glioma and the effects of CTLA-4 on prognosis in patients wit...

    Authors: Fangkun Liu, Jing Huang, Xuming Liu, Quan Cheng, Chengke Luo and Zhixiong Liu

    Citation: Cancer Cell International 2020 20:7

    Content type: Primary research

    Published on:

  19. LncRNA Brain Cytoplasmic RNA 1 (BCYRN1) has been certified to modulate cancer cells growth and aggressiveness in several tumors. However, research about function of BCYRN1 in hepatocellular carcinoma (HCC) is ...

    Authors: Shichao Ding, Yanfeng Jin, Qingzhi Hao, Yanmeng Kang and Ruiping Ma

    Citation: Cancer Cell International 2020 20:6

    Content type: Primary research

    Published on:

  20. Ovarian cancer (OC) is a common fatal malignant tumor of female reproductive system worldwide. Growing studies have proofed that circular RNAs (circRNAs) engage in the regulation of various types of cancers. H...

    Authors: Wumei Lin, Haiyan Ye, Keli You and Le Chen

    Citation: Cancer Cell International 2020 20:5

    Content type: Primary research

    Published on:

  21. The issue of drug resistance in gastric cancer has attracted global attention. TSPAN9, a 4-transmembrane protein that plays an important role in tumor progression and signal transduction, has been found to be ...

    Authors: Yaoyue Qi, Weiwei Qi, Shihai Liu, Libin Sun, Aiping Ding, Guohong Yu, Hui Li, Yixuan Wang, Wensheng Qiu and Jing Lv

    Citation: Cancer Cell International 2020 20:4

    Content type: Primary research

    Published on:

  22. Ubiquilin-4 (UBQLN4) is a member of the ubiquitin–proteasome system that is usually upregulated in many tumor cells. Its overexpression has been associated with poor disease outcomes in various cancer diseases...

    Authors: Yan Yu, Penglin Xu, Guangying Cui, Xiaodong Xu, Kongfei Li, Xiaolong Chen and Jie Bao

    Citation: Cancer Cell International 2020 20:3

    Content type: Primary research

    Published on:

  23. Lung adenocarcinoma (LUAD), a widespread histopathological subtype of lung cancer, is deemed as a malignant tumor with a peak risk of mortality. Emerged as RNA with a loop structure that depleted protein codin...

    Authors: Nan Gao and Baoguo Ye

    Citation: Cancer Cell International 2020 20:2

    Content type: Primary research

    Published on:

  24. Gliomas account for the major part of primary brain tumors. Based on their histology and molecular alternations, adult gliomas have been classified into four grades, each with distinct biology and outcome. Pre...

    Authors: Wenxin Zeng, Zhaohua Tang, Yongguo Li, Guangnian Yin, Zili Liu, Jie Gao, Yan Chen and Feilan Chen

    Citation: Cancer Cell International 2020 20:1

    Content type: Primary research

    Published on:

  25. Increasing studies have suggested that aberrant expression of microRNAs might play essential roles in the progression of cancers. In this study, we sought to construct a high-specific and superior microRNAs si...

    Authors: Rong Ma, Yanyun Zhao, Miao He, Hongliang Zhao, Yifan Zhang, Shuqi Zhou, Mengcong Gao, Di Di, Jue Wang, Jian Ding and Minjie Wei

    Citation: Cancer Cell International 2019 19:360

    Content type: Primary research

    Published on:

  26. The editor has retracted this article [1] because Fig. 2f has been duplicated from Fig. 6j in a previously published article [2]. In addition, the article contains sections that substantially overlap with a pr...

    Authors: Jie Song, Wei Zhao, Chang Lu and Xue Shao

    Citation: Cancer Cell International 2019 19:359

    Content type: Retraction Note

    Published on:

    The original article was published in Cancer Cell International 2019 19:60

  27. The editor has retracted this article [1] because Figures 2 and 4 contain duplicated and modified figures from [2–4]. The data reported in this article are therefore unreliable.

    Authors: Xiaoyan Ding, Wei Sun and Jinglong Chen

    Citation: Cancer Cell International 2019 19:358

    Content type: Retraction Note

    Published on:

    The original article was published in Cancer Cell International 2018 18:176

  28. Neuroblastoma (NB) is one of most common childhood tumors with high mortality among children worldwide. microRNAs (miRNAs) have been reported to play essential roles in the pathogenesis and therapeutics of NB....

    Authors: Fengxia Mao, Ju Zhang, Xinru Cheng and Qianya Xu

    Citation: Cancer Cell International 2019 19:357

    Content type: Primary research

    Published on:

  29. The DNA damage and repair pathway is considered a promising target for developing strategies against cancer. RAD51, also known as RECA, is a recombinase that performs the critical step in homologous recombinat...

    Authors: Xiaomeng Zhang, Ningyi Ma, Weiqiang Yao, Shuo Li and Zhigang Ren

    Citation: Cancer Cell International 2019 19:356

    Content type: Primary research

    Published on:

  30. The purpose of this study was to build functional nomograms based on significant clinicopathological features to predict cause-specific survival (CSS) and overall survival (OS) in patients with stage I–III col...

    Authors: Zheng Zhou, Shaobo Mo, Weixing Dai, Wenqiang Xiang, Lingyu Han, Qingguo Li, Renjie Wang, Lu Liu, Long Zhang, Sanjun Cai and Guoxiang Cai

    Citation: Cancer Cell International 2019 19:355

    Content type: Primary research

    Published on:

  31. miR-100 has been reported to closely associate with gastric cancer (GC) initiation and progression. However, the underlying mechanism of miR-100-3p in GC is still largely unclear. In this study, we intend to s...

    Authors: Chun-Wei Peng, Ling-Xiao Yue, Yuan-Qin Zhou, Sai Tang, Chen Kan, Lei-Ming Xia, Fan Yang and Si-Ying Wang

    Citation: Cancer Cell International 2019 19:354

    Content type: Primary research

    Published on:

  32. Gastric cancer (GC) is a common-sighted cancer which is hard to cure over the world. Substantial researches revealed that long non-coding RNAs (lncRNAs) were fundamental regulators in the process of cancers. N...

    Authors: Zhaosheng Chen, Honglei Wu, Zhen Zhang, Guangchun Li and Bin Liu

    Citation: Cancer Cell International 2019 19:351

    Content type: Primary research

    Published on:

  33. Gastric cancer (GC) is one common cancer which occurs in the stomach leading to high mortality around the world. Long non-coding RNAs (lncRNAs) were found overexpressed or silenced in the occurrence and progre...

    Authors: Hua Zhang, Haitao Huang, Xiaomei Xu, Haiying Wang, Jianxiang Wang, Zuoyi Yao, Xiaoyan Xu, Qian Wu and Fenlan Xu

    Citation: Cancer Cell International 2019 19:350

    Content type: Primary research

    Published on:

  34. Over the years, long non-coding RNAs (lncRNAs) have been clarified in malignancies, this research was focused on the role of lncRNA cartilage injury-related (lncRNA-CIR) in osteosarcoma cells.

    Authors: Shiwei Liu, Jingchao Li, Liang Kang, Yueyang Tian and Yuan Xue

    Citation: Cancer Cell International 2019 19:349

    Content type: Primary research

    Published on:

  35. Casticin, an isoflavone compound extracted from the herb Fructus Viticis, has demonstrated anti-inflammatory and anticancer activities and properties. The aim of this study was to investigate the effects and m...

    Authors: Jingxian Liu, Jinghong Yang, Yuhe Hou, Zhenwei Zhu, Jie He, Hao Zhao, Xidong Ye, Dengke Li, Zhaohui Wu, Zhongxi Huang, Bingtao Hao and Kaitai Yao

    Citation: Cancer Cell International 2019 19:348

    Content type: Primary research

    Published on:

  36. Ovarian cancer (OC) is a gynecological malignancy with a high mortality. Cisplatin-based treatment is the typical treatment regimen for OC patients; however, it may cause unfavorable resistance. The current st...

    Authors: Hua Guo, Chunfang Ha, Hui Dong, Zhijuan Yang, Yuan Ma and Yonghui Ding

    Citation: Cancer Cell International 2019 19:347

    Content type: Primary research

    Published on:

  37. Treatments that generate T cell-mediated immunity to a patient’s unique neoantigens are the current holy grail of cancer immunotherapy. In particular, treatments that do not require cumbersome and individualiz...

    Authors: Stephen M. Shaw, Jenny Middleton, Kim Wigglesworth, Amber Charlemagne, Oliver Schulz, Melanie S. Glossop, Giles F. Whalen, Robert Old, Mike Westby, Chris Pickford, Rinat Tabakman, Irit Carmi-Levy, Abi Vainstein, Ella Sorani, Arik A. Zur and Sascha A. Kristian

    Citation: Cancer Cell International 2019 19:346

    Content type: Primary research

    Published on:

  38. Glioblastoma has been seen as the most common malignancy of brain tumor. Emerging reports has claimed that SNHG29 (LRRC75A-AS1) was involved in several biological processes via modulation of signaling pathway,...

    Authors: Lizhang Han, Zhonggang Li, Yuquan Jiang, Zheng Jiang and Ling Tang

    Citation: Cancer Cell International 2019 19:345

    Content type: Primary research

    Published on:

  39. Gastric cancer (GC) is one of the most common gastrointestinal malignancies worldwide. Emerging evidence indicates that hyperglycemia promotes tumor progression, especially the processes of migration, invasion...

    Authors: Xin Xu, Bang Chen, Shaopu Zhu, Jiawei Zhang, Xiaobo He, Guodong Cao and Bo Chen

    Citation: Cancer Cell International 2019 19:344

    Content type: Primary research

    Published on:

  40. The progression of ductal carcinoma in situ (DCIS) into invasive ductal carcinoma (IDC) is prevented by normal breast myoepithelial cells. Studies have suggested that EMT-associated genes were enriched in IDC ...

    Authors: Li Wang, Cong Xu, Xia Liu, Yang Yang, Lu Cao, Guomin Xiang, Fang Liu, Shuling Wang, Jing Liu, Qingxiang Meng, Jiao Jiao and Yun Niu

    Citation: Cancer Cell International 2019 19:343

    Content type: Primary research

    Published on:

  41. As a novel type of isothiocyanate derived from radish seeds from cruciferous vegetables, sulforaphene (SFE, 4-methylsufinyl-3-butenyl isothiocyanate) has various important biological effects, such as anti-oxid...

    Authors: Chengjuan Zhang, Junxia Zhang, Qiong Wu, Benling Xu, Guoguo Jin, Yan Qiao, Simin Zhao, Yang Yang, Jinwen Shang, Xiaofang Li and Kangdong Liu

    Citation: Cancer Cell International 2019 19:342

    Content type: Primary research

    Published on:

  42. Circulating tumor cells (CTCs) are a rare subset of cells found in the blood of patients with solid tumors, which function as a seed for metastases. Cancer cells metastasize through the bloodstream either as s...

    Authors: Chang Yang, Bai-Rong Xia, Wei-Lin Jin and Ge Lou

    Citation: Cancer Cell International 2019 19:341

    Content type: Review

    Published on:

  43. Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide, especially in China, with high metastasis and poor prognosis. Recently, as the core component of the polycomb repressive complex...

    Authors: Xiaonian Zhu, Wei Luo, Chunhua Bei, Juan Kong, Shidong Zhang, Yuanyuan Fu, Di Li and Shengkui Tan

    Citation: Cancer Cell International 2019 19:340

    Content type: Primary research

    Published on:

  44. Ovarian cancer is one of the leading causes of female death worldwide, with a poor prognosis of advanced patients. Sevoflurane, a volatile anesthetic commonly used in clinical operations, has been reported to ...

    Authors: Chuanfeng Zhang, Baosheng Wang, Xiuqin Wang, Xiugui Sheng and Yongchun Cui

    Citation: Cancer Cell International 2019 19:339

    Content type: Primary research

    Published on:

  45. The dysregulation of circABCB10 may play an critical role in tumor progression. However, its function in liver cancer (HCC) is still unclear. Therefore, this experimental design is based on circABCB10 to explo...

    Authors: Yu Fu, Limin Cai, Xuexue Lei and Dunwei Wang

    Citation: Cancer Cell International 2019 19:338

    Content type: Primary research

    Published on:

  46. Muscle-invasive bladder cancer (MIBC) is originated in the muscle wall of the bladder, and is the ninth most common malignancy worldwide. However, there are no reliable, accurate and robust gene signatures for...

    Authors: Ping-Bao Zhang, Zi-Li Huang, Yong-Hua Xu, Jin Huang, Xin-Yu Huang and Xiu-Yan Huang

    Citation: Cancer Cell International 2019 19:337

    Content type: Primary research

    Published on:

  47. Autophagy is an evolutionarily conserved process through which cells degrade and recycle cytoplasm. The relation among autophagy, apoptosis and tumor is highly controversial until now and the molecular mechani...

    Authors: Jing Liu, Shuaiyu Long, Huanan Wang, Nannan Liu, Chuchu Zhang, Lingling Zhang and Yingjie Zhang

    Citation: Cancer Cell International 2019 19:336

    Content type: Primary research

    Published on:

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