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  1. Content type: Primary Research

    Dysregulated expression of long non-coding RNAs (lncRNAs) has been reported in the pathogenesis and progression of multiple cancers, including hepatocellular carcinoma (HCC). LncRNA CTD-2547G23.4 is a novel ln...

    Authors: Dong-yue Wen, Peng Lin, Hai-wei Liang, Xia Yang, Hai-yuan Li, Yun He, Hong Yang and Gang Chen

    Citation: Cancer Cell International 2018 18:74

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  2. Content type: Correction

    Upon publication of the original article [1] it was highlighted by the authors that a grant awarded to support the research work of the study was missed in the Funding Acknowledgements of their manuscript. It ...

    Authors: Du-Chu Chen, You-De Liang, Liang Peng, Yi-Ze Wang, Chun-Zhi Ai, Xin-Xing Zhu, Ya-Wei Yan, Yasmeen Saeed, Bin Yu, Jingying Huang, Yuxin Gao, Jiaqi Liu, Yi-Zhou Jiang, Min Liu and Demeng Chen

    Citation: Cancer Cell International 2018 18:73

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    The original article was published in Cancer Cell International 2017 17:103

  3. Content type: Primary Research

    Castrate resistant prostate cancer (CRPC) is often driven by constitutively active forms of the androgen receptor such as the V7 splice variant (AR-V7) and commonly becomes resistant to established hormonal th...

    Authors: Sergio Regufe da Mota, Sarah Bailey, Rosemary A. Strivens, Annette L. Hayden, Leon R. Douglas, Patrick J. Duriez, M. Teresa Borrello, Hanae Benelkebir, A. Ganesan, Graham Packham and Simon J. Crabb

    Citation: Cancer Cell International 2018 18:71

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  4. Content type: Primary Research

    Intrinsic chemoresistance of glioblastoma (GBM) is frequently owed to activation of the PI3K and MEK/ERK pathways. These signaling cascades are tightly interconnected however the quantitative contribution of b...

    Authors: Bodo Haas, Veronika Klinger, Christina Keksel, Verena Bonigut, Daniela Kiefer, Julia Caspers, Julia Walther, Maria Wos-Maganga, Sandra Weickhardt, Gabriele Röhn, Marco Timmer, Roland Frötschl and Niels Eckstein

    Citation: Cancer Cell International 2018 18:69

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  5. Content type: Primary research

    To explore the genetic effect of rs2031920 and rs3813867 polymorphisms within the cytochrome P450 2E1 (CYP2E1) gene on the risk of squamous cell carcinoma (SCC), a meta-analysis was performed.

    Authors: Hai Zhang, Haiyan Li and Huanxin Yu

    Citation: Cancer Cell International 2018 18:67

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  6. Content type: Primary research

    Ovarian cancer is the most lethal gynaecological malignancy. Chemotherapy is the main stay of treatment for metastatic disease, with modest response rates but significant side effects. Therefore, there is a ne...

    Authors: Karen K. L. Chan, Michelle K. Y. Siu, Yu-xin Jiang, Jing-jing Wang, Thomas H. Y. Leung and Hextan Y. S. Ngan

    Citation: Cancer Cell International 2018 18:65

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  7. Content type: Primary research

    Abnormal microRNA expression is closely related to cancer occurrence and development. miR-365a-3p plays an oncogenic role in skin cancer, but its role in lung cancer remains unclear. In this study, we aimed to...

    Authors: Yuhuan Wang, Shuhua Zhang, Hejing Bao, Shukun Mu, Baishen Zhang, Hao Ma and Shudong Ma

    Citation: Cancer Cell International 2018 18:64

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  8. Content type: Primary research

    MicroRNAs deregulation are common in human tumor progression. miR-1236-3p has been reported to function as tumor suppressor microRNA in various malignancies. The aim of this study was to demonstrate the downre...

    Authors: Jia-Xiang An, Ming-Hui Ma, Chun-Dong Zhang, Shuai Shao, Nuo-Ming Zhou and Dong-Qiu Dai

    Citation: Cancer Cell International 2018 18:66

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  9. Content type: Primary Research

    A growing field of evidence suggests the involvement of oncogenic receptor tyrosine kinases (RTKs) in cell transformation. Deregulated activity of RTKs in tumors can determine disease progression and therapeut...

    Authors: Sanja Aveic, Marcella Pantile, Pierfrancesco Polo, Viktoryia Sidarovich, Marilena De Mariano, Alessandro Quattrone, Luca Longo and Gian Paolo Tonini

    Citation: Cancer Cell International 2018 18:63

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  10. Content type: Primary Research

    Despite recent advances, multiple myeloma (MM) remains incurable. However, the appearance of allogeneic stem cell transplantation (allo-SCT) through graft-versus-myeloma effect provides a potential way to cure...

    Authors: Xuejiao Yin, Liang Tang, Fengjuan Fan, Qinyue Jiang, Chunyan Sun and Yu Hu

    Citation: Cancer Cell International 2018 18:62

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  11. Content type: Primary Research

    Immunotoxins are typical therapeutic drugs that can target cancer cells. They exploit the affinity of specific monoclonal antibodies or ligands to cancer cells to deliver a conjugated protein toxin to target s...

    Authors: Miaonan Sun, Liankun Sun, Dejun Sun, Chunmei Zhang and Mei Li

    Citation: Cancer Cell International 2018 18:58

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  12. Content type: Primary Research

    Recently, long non-coding RNA (lncRNA) MIAT has been demonstrated as an oncogenic gene in several types of cancer. However, the role and mechanism of MIAT in colorectal cancer (CRC) have not been investigated.

    Authors: Zhaoxia Liu, Hai Wang, Hongwei Cai, Ye Hong, Yan Li, Dongming Su and Zhining Fan

    Citation: Cancer Cell International 2018 18:59

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  13. Content type: Primary Research

    Metastatic dissemination of solid tumors is often initiated by reactivation of an embryonic development program, epithelial-to-mesenchymal-transition (EMT). EMT has been associated with acquiring invasiveness ...

    Authors: Mamta Singla, Ajay Kumar, Amanjit Bal, Subhendu Sarkar and Shalmoli Bhattacharyya

    Citation: Cancer Cell International 2018 18:57

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  14. Content type: Primary Research

    Renal cell carcinoma accounts for 2–3% of all cancers and metastasis increased the malignancy of renal cancer. However, the role of methylation in metastasis of renal cancer is poorly understood.

    Authors: Jianbo Zheng, Yanhui Mei, Ping Xiang, Guangsheng Zhai, Ning Zhao, Chuanbing Xu, Min Liu, Zhengsheng Pan, Kai Tang and Dongsheng Jia

    Citation: Cancer Cell International 2018 18:56

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  15. Content type: Correction

    After publication of the original article (1) it was noted that the author details and affiliations of this manuscript contained minor errors in the institution addresses.

    Authors: Yue Li, You Li, Yao Chen, Qian Xie, Ningning Dong, Yanjun Gao, Huan Deng, Chunhua Lu and Suihai Wang

    Citation: Cancer Cell International 2018 18:55

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    The original article was published in Cancer Cell International 2017 17:102

  16. Content type: Primary Research

    Signal transducer and activator of transcription 3 (STAT3) is persistently activated in a wide variety of epithelial cancers. Aberrant activity of STAT3 correlates with tumor growth, invasion and metastasis, w...

    Authors: Chao Zhou, Jie Ma, Mengyuan Su, Dan Shao, Jianan Zhao, Tongjian Zhao, Zhuoyao Song, Yan Meng and Ping Jiao

    Citation: Cancer Cell International 2018 18:53

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  17. Content type: Primary research

    Paired box gene 8 (PAX8) is expressed in and indispensable to thyroid development. MiR-144-3p is found dys-regulated in cancers, and it can block the expression of target gens. This study sought to understand ...

    Authors: Chang Liu, Chang Su, Yanchun Chen and Guang Li

    Citation: Cancer Cell International 2018 18:54

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  18. Content type: Primary research

    Osteosarcoma (OS) is a rare, malignant bone tumor that primarily affects adolescents and has a high degree of malignancy and high incidence of recurrence and metastasis. Our study aimed to explore the role of ...

    Authors: Riliang Cao, Jianli Shao, Yabin Hu, Liang Wang, Zhizhong Li, Guodong Sun and Xiaoliang Gao

    Citation: Cancer Cell International 2018 18:49

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  19. Content type: Primary Research

    Endometrial cancer (EC) is the fourth most common malignancy of the female genital tract worldwide. MicroRNAs are important gene regulators with critical roles in diverse biological processes, including tumori...

    Authors: JinHui Liu, ChunYu Li, Yi Jiang, YiCong Wan, ShuLin Zhou and WenJun Cheng

    Citation: Cancer Cell International 2018 18:51

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