Primary Research
PA-MSHA induces apoptosis and suppresses metastasis by tumor associated macrophages in bladder cancer cells
Published on: 17 August 2017
Featured article: Chemotherapy and tumor microenvironment of pancreatic cancer
In this article, Liu et al. review the following four aspects; (1) clinical landmark advances of chemotherapy in pancreatic cancer, since 2000; (2) interactions and mechanisms between stromal cells and pancreatic cancer cells; (3) remodeling effects and mechanisms of chemotherapy on TME; (4) targeting stromal components in pancreatic cancer.
Articles
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Primary Research
Aberrantly methylated-differentially expressed genes and pathways in colorectal cancer
Published on: 7 August 2017
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Primary Research
The role of REST and HDAC2 in epigenetic dysregulation of Nav1.5 and nNav1.5 expression in breast cancer
Published on: 1 August 2017
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Primary Research
Regulatory effects of COL1A1 on apoptosis induced by radiation in cervical cancer cells
Published on: 28 July 2017
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Review
Understanding the colon cancer stem cells and perspectives on treatment
Published on: 28 January 2015
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Review
Acidic extracellular microenvironment and cancer
Published on: 3 September 2013
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Aims and scope
Cancer Cell International publishes articles on all aspects of cancer cell biology, originating largely from work using cell culture techniques.
Featured article: Differential expression of VEGFR2 protein in HER2 positive primary human breast cancer
In this study, Nasir et al. aim to characterize the patterns of pathologic angiogenesis in various therapeutically relevant molecular breast cancer subtypes (HR+, HER2+, TNBC) by evaluation of vascular density and immunohistochemical expression of VEGFR2 protein in a retrospective series of primary human breast cancer tissues.
Featured article - HOTAIR: a key regulator in gynecologic cancers
HOTAIR (HOX transcript antisense) promotes tumor invasion and metastasis by silencing tumor suppressors, and activating oncogenes and signaling pathways. HOTAIR is deregulated in many human cancers; despite its critical roles in health and disease, the underlying mechanisms governing HOTAIR function are unknown. In this review, Li et al. summarize the recent findings on the roles of HOTAIR in gynecologic cancers.
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