Cancer Cell International

Featured article: Dual EGFR and BRAF blockade overcomes resistance to vemurafenib in BRAF mutated TC cells

In this study, Notarangelo et al., evaluated the hypothesis that the exposure of BRAF-mutated thyroid carcinoma (TC) cells to vemurafenib results in EGFR feedback activation and that dual EGFR and BRAF blockade is superior to single agents.

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Primary Research

Avenanthramide-C reduces the viability of MDA-MB-231 breast cancer cells through an apoptotic mechanism

Jordan Hastings and Jason Kenealey

Published on: 18 October 2017
Primary Research

The role of miR-485-5p/NUDT1 axis in gastric cancer

Jingjing Duan, Haiyang Zhang, Shuang Li, Xinyi Wang, Haiou Yang, Shunchang Jiao and Yi Ba

Published on: 17 October 2017
Primary Research

Integrated genomic characterization of cancer genes in glioma

Aijun Liang, Bin Zhou and Wei Sun

Published on: 13 October 2017
Primary Research

Down-regulation of IFITM1 and its growth inhibitory role in cervical squamous cell carcinoma

Weinan Zheng, Zhimin Zhao, Xinan Yi, Qiangqiang Zuo, Hongtao Li, Xiaoqing Guo, Dongmei Li, Hongchang He, Zemin Pan, Peiwen Fan, Feng Li, Yanhong Liao and Renfu Shao

Published on: 10 October 2017
Primary Research

Identification of genes and pathways potentially related to PHF20 by gene expression profile analysis of glioblastoma U87 cell line

Tianlong Liu, Tiejun Zhang, Feng Zhou, Jitao Wang, Xiaohu Zhai, Nan Mu, Jongsun Park, Minna Liu, Wenxing Liu, Peijin Shang, Yi Ding, Aidong Wen and Yuwen Li

Published on: 4 October 2017

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Review

Understanding the colon cancer stem cells and perspectives on treatment

Elsa N Garza-Treviño, Salvador L Said-Fernández and Herminia G Martínez-Rodríguez

Published on: 28 January 2015
Review

Acidic extracellular microenvironment and cancer

Yasumasa Kato, Shigeyuki Ozawa, Chihiro Miyamoto, Yojiro Maehata, Atsuko Suzuki, Toyonobu Maeda and Yuh Baba

Published on: 3 September 2013
Primary research

B7-H3 promotes aggression and invasion of hepatocellular carcinoma by targeting epithelial-to-mesenchymal transition via JAK2/STAT3/Slug signaling pathway

Fu-biao Kang, Ling Wang, Heng-chuan Jia, Dong Li, Hai-jun Li, Yin-ge Zhang and Dian-xing Sun

Published on: 21 April 2015
Primary research

Treatment with the PARP inhibitor, niraparib, sensitizes colorectal cancer cell lines to irinotecan regardless of MSI/MSS status

Sybil M Genther Williams, Apryle M Kuznicki, Paula Andrade, Brian M Dolinski, Cem Elbi, Ronan C O’Hagan and Carlo Toniatti

Published on: 4 February 2015
Review

Role of stem cells in cancer therapy and cancer stem cells: a review

Jayesh Sagar, Boussad Chaib, Kevin Sales, Marc Winslet and Alexander Seifalian

Published on: 4 June 2007

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Aims and scope

Cancer Cell International publishes articles on all aspects of cancer cell biology, originating largely from, but not limited to, work using cell culture techniques.

Editors-in-Chief

Y Eugene Chin, Shanghai Institute of Biological Sciences, China
Domenico Coppola, Moffitt Cancer Center, USA

Featured article: DMD transcripts in CRL-2061 RMS cells show high levels of intron retention

The DMD gene encoding dystrophin is mutated in Duchenne muscular dystrophy and has been shown to act as a tumor suppressor. Rhabdomyosarcoma (RMS) is a mesodermal sarcoma that shares characteristics of skeletal muscle precursors. In this article, Niba et al., analyze DMD products in CRL-2061 cells established from alveolar rhabdomyosarcoma.