Featured article: Omics-based molecular techniques in oral pathology centred cancer

African clinicAs the field of oral pathology expands in Africa, currently emerging omics-based technologies are, in principle, poised to improve disease diagnosis and treatment. In this review, Adeola et al. examine the challenges and prospects of using omics-based techniques in a resource limited setting and provide recommendations for the future.

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Cancer Cell International publishes articles on all aspects of cancer cell biology, originating largely from work using cell culture techniques. 

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Featured article: Suppression of endothelial cell migration reversed by epithelial ovarian cancer exosomal lncRNA

Featured imageEpithelial ovarian cancer (EOC) has the highest mortality rate of all gynecological malignancies. In this article, Wu et al. study the mechanism by which EOC-derived exosomes restore the migration of endothelial cells that is suppressed by TAM-derived exosomes.

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Featured article - HOTAIR: a key regulator in gynecologic cancers

New Content ItemHOTAIR (HOX transcript antisense) promotes tumor invasion and metastasis by silencing tumor suppressors, and activating oncogenes and signaling pathways. HOTAIR is deregulated in many human cancers; despite its critical roles in health and disease, the underlying mechanisms governing HOTAIR function are unknown. In this review, Li et al. summarize the recent findings on the roles of HOTAIR in gynecologic cancers.

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