Cancer Cell International

Article highlight: Molecular biomarkers in gastro-esophageal cancer

Significant progress has been made in recent years in dissecting the genomic makeup of gastro-esophageal adenocarcinomas (GEA), which have been found to be highly heterogeneous malignances, representing a challenge for biomarkers discovery and targeted treatment development. This invited review, by Drs Battaglin, Naseem, Puccini & Lenz focuses on an overview of established and novel promising biomarkers in GEA, covering recent molecular classifications from TCGA and ACRG. The review appears in Emerging biomarkers in oncology research and practice, guest edited by Dr. Aejaz Nasir.

Content type: Primary research
| 17 August 2018

Establishment and characterization of three stable Basal/HER2-positive breast cancer cell lines derived from Chinese breast carcinoma with identical missense mutations in the DNA-binding domain of TP53

Authors: Fei Zhou, Yanhua Zhang, Xiufang Xu, Jingfeng Luo, Fang Yang, Linbo Wang, Shuduo Xie, Jihong Sun and Xiaoming Yang
Content type: Primary research
| 14 August 2018

TAZ inhibition promotes IL-2-induced apoptosis of hepatocellular carcinoma cells by activating the JNK/F-actin/mitochondrial fission pathway

Authors: Kaihua Ji, Kaili Lin, Yan Wang, Liqing Du, Chang Xu, Ningning He, Jinhan Wang, Yang Liu and Qiang Liu
Content type: Primary research
| 13 August 2018

MicroRNA-524 promotes cell proliferation by down-regulating PTEN expression in osteosarcoma

Authors: Ming Zhuang, Xubin Qiu, Dong Cheng, Chenlei Zhu and Liang Chen
Content type: Primary research
| 13 August 2018

Clinical significance of serum soluble B7-H3 in patients with osteosarcoma

Authors: Ling Wang, Fu-biao Kang, Guo-chuan Zhang, Juan Wang, Ming-fang Xie and Ying-ze Zhang
Content type: Primary research
| 13 August 2018

Circ-ZEB1.33 promotes the proliferation of human HCC by sponging miR-200a-3p and upregulating CDK6

Authors: Yuhua Gong, Jinzhong Mao, Di Wu, Xuemei Wang, Long Li, Liang Zhu and Rong Song

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Content type: Review
| 3 September 2013

Acidic extracellular microenvironment and cancer

Authors: Yasumasa Kato, Shigeyuki Ozawa, Chihiro Miyamoto, Yojiro Maehata, Atsuko Suzuki, Toyonobu Maeda and Yuh Baba
Content type: Review
| 28 January 2015

Understanding the colon cancer stem cells and perspectives on treatment

Authors: Elsa N Garza-Treviño, Salvador L Said-Fernández and Herminia G Martínez-Rodríguez
Content type: Review
| 4 June 2007

Role of stem cells in cancer therapy and cancer stem cells: a review

Authors: Jayesh Sagar, Boussad Chaib, Kevin Sales, Marc Winslet and Alexander Seifalian
Content type: Primary research
| 21 April 2015

B7-H3 promotes aggression and invasion of hepatocellular carcinoma by targeting epithelial-to-mesenchymal transition via JAK2/STAT3/Slug signaling pathway

Authors: Fu-biao Kang, Ling Wang, Heng-chuan Jia, Dong Li, Hai-jun Li, Yin-ge Zhang and Dian-xing Sun
Content type: Primary research
| 4 February 2015

Treatment with the PARP inhibitor, niraparib, sensitizes colorectal cancer cell lines to irinotecan regardless of MSI/MSS status

Authors: Sybil M Genther Williams, Apryle M Kuznicki, Paula Andrade, Brian M Dolinski, Cem Elbi, Ronan C O’Hagan and Carlo Toniatti

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Editors' pick: Inhibition of the PI3K but not the MEK/ERK pathway sensitizes human glioma cells to alkylating drugs

Aims and scope

Cancer Cell International publishes articles on all aspects of cancer cell biology, originating largely from, but not limited to, work using cell culture techniques.

Editors-in-Chief

Y Eugene Chin, Shanghai Institute of Biological Sciences, China
Domenico Coppola, Moffitt Cancer Center, USA

Associate Editor spotlight

Marilin Rosa

Dr. Marilin Rosa specializes in Breast Pathology and Cytopathology and serves as the Section Head of Breast Pathology at Moffitt Cancer Center and Research Institute in Tampa, Florida, USA. Dr. Rosa is also program director of the Breast Pathology Fellowship program at Moffitt. Her expertise is in breast cancer diagnosis, research, and education. Dr. Rosa’s research interests are identifying diagnostic, prognostic, and predictive biomarkers for breast cancer as well as studying cancer impact in low-resource/ minority populations.

Editorial Board spotlight

Go J. Yoshida

Dr. Go J. Yoshida graduated from Keio University School of Medicine in 2010 and obtained his PhD in 2013 with research on redox stress regulation in gastric and breast cancer stem cells through CD44 variant-xCT interaction. Since 2014, he has been working mainly on the pathophysiological significance of autophagy at the Medical Research Institute, Tokyo Medical and Dental University. He has recently reported the therapeutic potential of autophagic cell death in glioblastoma stem cells.

Cancer Cell International

Article highlight: Molecular biomarkers in gastro-esophageal cancer

Articles

Establishment and characterization of three stable Basal/HER2-positive breast cancer cell lines derived from Chinese breast carcinoma with identical missense mutations in the DNA-binding domain of TP53

TAZ inhibition promotes IL-2-induced apoptosis of hepatocellular carcinoma cells by activating the JNK/F-actin/mitochondrial fission pathway

MicroRNA-524 promotes cell proliferation by down-regulating PTEN expression in osteosarcoma

Clinical significance of serum soluble B7-H3 in patients with osteosarcoma

Circ-ZEB1.33 promotes the proliferation of human HCC by sponging miR-200a-3p and upregulating CDK6

Acidic extracellular microenvironment and cancer

Understanding the colon cancer stem cells and perspectives on treatment

Role of stem cells in cancer therapy and cancer stem cells: a review

B7-H3 promotes aggression and invasion of hepatocellular carcinoma by targeting epithelial-to-mesenchymal transition via JAK2/STAT3/Slug signaling pathway

Treatment with the PARP inhibitor, niraparib, sensitizes colorectal cancer cell lines to irinotecan regardless of MSI/MSS status

Editors' pick: Inhibition of the PI3K but not the MEK/ERK pathway sensitizes human glioma cells to alkylating drugs

Aims and scope

Editors-in-Chief

Associate Editor spotlight

Marilin Rosa

Editorial Board spotlight

Go J. Yoshida

2017 Journal Metrics

Cancer Cell International

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