Cancer Cell International

2021 marked the 20th year since Cancer Cell International published its very first articles. To mark the occasion, we're looking back at the journal's milestone achievements and highlighting some of the best content from the past 20 years.

Our milestones

^{Click on the infographic above for a downloadable version and to view the relevant articles.}

Anniversary video

Click here to watch our 20th anniversary video on YouTube.

Our top ranked articles of all time

Article	Publication year
Acidic extracellular microenvironment and cancer by Y. Kato et al.	2013
MicroRNA (miRNA) in cancer by K. B. Reddy	2015
ABC transporters as multidrug resistance mechanisms and the development of chemosensitizers for their reversal by C. Choi	2005
Tumor suppressor gene E-cadherin and its role in normal and malignant cells by N. Pećina-Šlaus	2003
Survivin: a unique target for tumor therapy by H. Garg et al.	2016

Article	Publication year
Role of stem cells in cancer therapy and cancer stem cells: a review by J. Sagar et al.	2007
Tumor suppressor gene E-cadherin and its role in normal and malignant cells by N. Pećina-Šlaus	2003
Stem cells, senescence, neosis and self-renewal in cancer by R. Rajaraman et al.	2006
Acidic extracellular microenvironment and cancer by Y. Kato et al.	2013
Real-time RT-PCR analysis of mRNA decay: half-life of Beta-actin mRNA in human leukemia CCRF-CEM and Nalm-6 cell lines by G. J. Leclerc et al.	2002

Article	Publication year
A humanized anti-CD26 monoclonal antibody inhibits cell growth of malignant mesothelioma via retarded G2/M cell cycle transition by M. Hayashi et al.	2016
Mitochondrial structure alteration in human prostate cancer cells upon initial interaction with a chemopreventive agent phenethyl isothiocyanate by C. Xue et al.	2014
Inhibition of human lung cancer cell proliferation and survival by wine by C. C. Barron et al.	2014
Synergistic effect of paclitaxel and epigenetic agent phenethyl isothiocyanate on growth inhibition, cell cycle arrest and apoptosis in breast cancer cells by K. Liu et al.	2013
Bioluminescence imaging reveals inhibition of tumor cell proliferation by Alzheimer's amyloid beta protein by H. Zhao et al.	2009

Comments from our community

New Content Item "It has been exciting to see the growth of Cancer Cell International journal over the years. The journal's focus has transitioned from pure basic science to basic science and translational research which has offered a lot of opportunities to contribute to the prevention and cure of cancer."
– Dr. Domenico Coppola, Editor-in-Chief
Moffitt Cancer Center and Florida Digestive Health Specialists, USA

New Content Item "Cancer Cell International has successfully and significantly grown and influenced the cancer research community. For our 20th anniversary, we have started to focus on translational research – bridging the bench and the clinic."
– Dr. Yasumasa Kato, Editor-in-Chief
Ohu University, Japan