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Table 5 Immunohistochemically detected MLL2 expression in human colonic tissues

From: Epigenetic regulator MLL2 shows altered expression in cancer cell lines and tumors from human breast and colon

 

Nuclear MLL2 staining

Cytoplasmic MLL2 staining

Positive cases

35/66 (53%)

66/66 (100%)

Tumor vs. Benign

  

T < B

7/35 (20%)

3/66 (5%)

T = B

1/35 (3%)

0/66 (0%)

T > B

27/35 (77%)*

63/66 (95%)*

  1. Distribution of colon cancer cases based on nuclear and cytoplasmic MLL2 immunostaining in tumor versus benign tissue; * p < 0.05