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Table 2 Ngb, Cygb and CA IX expression in tissue microarrays of human primary brain tumors

From: Hypoxic regulation of cytoglobin and neuroglobin expression in human normal and tumor tissues

Pathology Grade Ngb Cygb CA IX
Astrocytoma of right temporal lobe II 2 1 0
Ganglioglioma of right frontal lobe - 3 1 0
Astrocytoma of left temporal lobe II 3 1 0
Astrocytoma of right frontal lobe I 2 2 0
Astrocytoma II 1 2 0
Astrocytoma I 3 2 0
Astrocytoma of frontal lobe I 3 1 0
Astrocytoma I 3 1 0
Astrocytoma of right temporal lobe II 2 1 0
Astrocytoma of brain I 2 1 0
Astrocytoma of left occipital parietal lobe II 2 3 0
Astrocytoma of right occipital lobe II 3 2 0
Ganglioglioma of left temporoparietal lobe - 3 2 1
Astrocytoma of fourth ventricle II 3 1 1
Astrocytoma of left temporal lobe II 5 2 0
Astrocytoma II 5 2 0
Astrocytoma of left parietal lobe III 3 2 0
Colloid cell hyperplasia of left brain - 5 3 0
Astrocytoma of right temporoparietal lobe III 4 2 0
Astrocytoma of frontal lobe III 3 1 0
Astrocytoma of foramen magnum III 1 0 2
Astrocytoma of left temporal lobe II 3 2 0
Astrocytoma II 3 2 0
Brain tissue - 3 4 1
Astrocytoma of right temporal lobe II 3 2 0
Astrocytoma of fourth ventricle II 3 1 0
Astrocytoma of right temporal lobe II 3 1 0
Astrocytoma III 2 3 0
Astrocytoma of left temporoparietal lobe II 3 2 0
Astrocytoma of right cerebral ventricle II 4 3 0
Oligodendroglioma of right frontal lobe - 4 4 0
Astrocytoma of brain III 4 2 0
Astrocytoma of brain III 3 4 0
Astrocytoma of left temporal lobe II 3 2 0
Astrocytoma of left temporal lobe II 2 2 0
Astrocytoma of intracranial II 3 2 0
Astrocytoma of cerebellum III 1 1 0
Astrocytoma of left temporal lobe III 1 1 0
Astrocytoma with necrosis of left frontal lobe III 3 2 1
Astrocytoma of left temporal lobe III 3 1 0
Astrocytoma of temporoparietal lobe III 4 2 0
Astrocytoma of right cerebelli III 2 2 0
Astrocytoma III 3 2 0
Astrocytoma III 4 4 0
Brain tissue with colloid cell hyperplasia of right temporal lobe - 4 NE 0
Astrocytoma III 2 2 0
Astrocytoma of brain III 2 2 0
Astrocytoma of left frontal lobe III 3 1 0
Astrocytoma of brain II 4 3 0
Astrocytoma of left frontal lobe III 2 1 0
Astrocytoma of left temporal lobe II 4 4 1
Astrocytoma of left occipital III 3 3 0
Astrocytoma of left temporal lobe III 4 4 0
Astrocytoma of right temporal lobe IV 3 4 0
Astrocytoma of left temporal lobe III 2 1 0
Astrocytoma of right temporal lobe III 1 1 0
Astrocytoma of right temporal lobe III 3 1 0
Astrocytoma of fourth ventricle IV 3 2 0
Astrocytoma II 3 3 0
Astrocytoma of temporal lobe IV 4 2 0
Tumor necrosis tissue of right frontal region - 4 5 1
Astrocytoma of left occipital parietal lobe III 4 5 1
Malignant oligodendroglioma - 2 2 0
Desmoplastic astrocytoma of left temporoparietal lobe - 3 5 0
Astrocytoma of intracranial II 3 2 0
Ependymoblastoma of posterior fossa - 3 2 0
Ependymoma of brain parietooccipital - 3 3 0
Ependymoma of brain - 3 2 0
Ependymoma of right parietal lobe - 4 4 0
Ependymoma of intracranial - 3 3 0
Matched cerebrum tissue of 1st tumor - 2 2 0
Matched cerebrum tissue of 2nd tumor - 3 3 0
Matched cerebrum tissue of 3rd tumor - 4 4 1
Matched cerebrum tissue of 4th tumor - 1 2 0
Normal cerebrum tissue - 1 2 0
Normal cerebrum tissue - 1 1 0
Normal cerebrum tissue - 5 2 0
Normal cerebrum tissue - 2 3 0
Normal cerebrum tissue - 3 4 0
Normal cerebellum tissue - 3 1 0
  1. Tissue microarrays constructed from cores obtained from various human primary brain cancers and normal adjacent brain were purchased from IMGENEX Corporation (San Diego, CA). Immunopositive staining for Ngb, Cygb and CA IX was assessed by two observers who noted the overall tissue staining and the presence of positively stained focal regions. Each section was assigned an overall score, where 0 = absence of positively stained cells; 1 = a few positive cells/regions ( < 10%); 2 = weak positive staining, occasional positive foci; 3 = intermediate staining, occasional positive foci ( < 50%); 4 = strongly positive in most of the section, several positive foci; and 5 = strongly positive throughout with many intensely