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Figure 3 | Cancer Cell International

Figure 3

From: α-TEA-induced death receptor dependent apoptosis involves activation of acid sphingomyelinase and elevated ceramide-enriched cell surface membranes

Figure 3

α-TEA induces accumulation of DR5, Fas, FADD and ceramide in cell surface membranes. A, B & C, Cells were treated with 40 μM α-TEA or vehicle (VEH) for 15 hrs and cellular localization of DR5, Fas, FADD (red channel) and ceramide (green channel) were detected by immunostaining in paraformaldehyde fixed cells. Merge = overlay of ceramide (green channel) + DAPI (blue channel) + DR5 or Fas, or FADD (red channel). All data are representative images of three separate experiments.

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