Figure 6

Dz13 reduces aggressiveness of ectopic osteosarcoma, prostate and breast tumour growths. Haematoxylin- and eosin-stained osteosarcoma (G292), prostate (PC3) and breast (MDA-MB231) tumour sections are shown. In the Dz13 cohorts, less aggressive tumour growth is noted as sparse cell density and smaller area of occupation. Arrowheads: black, areas of dense cell growth, white, areas of sparse cell growth. Scr, scrambled sequence oligonucleotide of Dz13. Scale bar = 25 μm. Representative images are shown. Scale bar = 25 μm, n = 5.