Figure 4From: Different metastasis promotive potency of small G-proteins RalA and RalB in in vivo hamster tumor modelInfluence of RalA and RalB activation on CD24, Cyclin D1, Cav-1 and MAPKs. (a) RalA upregulates expression of CD24. (b) Both Ral proteins stimulate Cyclin D1 expression. (c) RalB downregulates Caveolin-1 expression. (d, e) Neither of Ral proteins modulate ERK and p38 kinases phosphorylation. (f) JNK1 phosphorylation is equally stimulated in RalA- and RalB-expressing HET-SR cells.Back to article page