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Figure 4 | Cancer Cell International

Figure 4

From: Different metastasis promotive potency of small G-proteins RalA and RalB in in vivo hamster tumor model

Figure 4

Influence of RalA and RalB activation on CD24, Cyclin D1, Cav-1 and MAPKs. (a) RalA upregulates expression of CD24. (b) Both Ral proteins stimulate Cyclin D1 expression. (c) RalB downregulates Caveolin-1 expression. (d, e) Neither of Ral proteins modulate ERK and p38 kinases phosphorylation. (f) JNK1 phosphorylation is equally stimulated in RalA- and RalB-expressing HET-SR cells.

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