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Figure 4 | Cancer Cell International

Figure 4

From: 5-alpha-reductase type I (SRD5A1) is up-regulated in non-small cell lung cancer but does not impact proliferation, cell cycle distribution or apoptosis

Figure 4

Relative gene expression of SRD5A1 normalized to cyclophilin after 24 h of siRNA treatment in A549 (A) and NCI-H460 (B) cells. Experiments were performed in triplicate with 10 pmol siRNA and 5 μl Lipofectamine™ 2000. (A) A549: * significant difference to untreated (siRNA 1: P = 0.001), **significantly smaller than 5% (siRNA 2: P < 0.001, siRNA 3: P < 0.001). (B) NCI-H460: *significant difference to untreated (siRNA 1: P = 0.2, siRNA 2: P = 0.11), **significantly smaller than 5% (siRNA 3: P = 0.05).

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