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Table 2 In vitro growth inhibitory activity of the semi-purified fractions, F2 and F3, of Spongia officinalis: against the three human tumor cell lines A549 (lung cell carcinoma), HCT15 (colon cell carcinoma) and MCF7 (breast adenocarcinoma)

From: Evaluation of antiproliferative and anti-inflammatory activities of methanol extract and its fractions from the Mediterranean sponge

 

IC50 (μg/ml)

Fractions

A549

HCT15

MCF7

F2 fraction

1225

-

980

F3 fraction

231

212.5

72

  1. IC50: 50 percent inhibition of cell growth.