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Table 2 In vitro growth inhibitory activity of the semi-purified fractions, F2 and F3, of Spongia officinalis: against the three human tumor cell lines A549 (lung cell carcinoma), HCT15 (colon cell carcinoma) and MCF7 (breast adenocarcinoma)

From: Evaluation of antiproliferative and anti-inflammatory activities of methanol extract and its fractions from the Mediterranean sponge

  IC50 (μg/ml)
Fractions A549 HCT15 MCF7
F2 fraction 1225 - 980
F3 fraction 231 212.5 72
  1. IC50: 50 percent inhibition of cell growth.