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Table 3 In vitro colony inhibitory activity of the semi-purified fractions, F2 and F3, of Spongia officinalis against three human tumor cell lines: A549 (lung cell carcinoma), HCT15 (colon cell carcinoma) and MCF7 (breast adenocarcinoma)

From: Evaluation of antiproliferative and anti-inflammatory activities of methanol extract and its fractions from the Mediterranean sponge

  IC50 (μg/ml)
Fractions A549 HCT15 MCF7
F2 fraction 875 - 375
F3 fraction 137.5 139.25 37.5
  1. IC50: 50 percent inhibition of colony formation