Figure 1
From: Lycorine induces cell-cycle arrest in the G0/G1 phase in K562 cells via HDAC inhibition
Lycorine decreases K562 cell growth. (A) Effect of lycorine on the proliferation of K562 cells. Cells were cultivated in RPMI 1640 medium with indicated concentrations of lycorine for 24, 48, and 72 h. The cell density was counted by manual cell counting. (B) Effect of lycorine on the survival rate of K562 cells. Cells were cultivated in RPMI 1640 medium with indicated concentrations of lycorine for 24 and 48 h. The cell survival rate was calculated by CCK-8 method. Each value represents the mean ± S.D. of three independent experiments.