Skip to main content

Table 1 Clinical features of the Patients with DMNT3A mutations

From: DNMT3A mutations and clinical features in Chinese patients with acute myeloid leukemia

No Age sex FAB Cytogenetics WBC X10^9/L CD33+/CD34+ DNMT3A Chemo-response result
7 65 F M1 normal 36.6 6%/92% 2645 G > A CR Dead(12 M)
19 72 M M2 normal 57.2 99%/32% 914 G > A No Dead(6 M)
22 55 M M5 normal 112.9 99%/16% 2645 G > A CR Alive(SCT)
38 58 F M5 t(6;9) 12.1 56%/55% 2096 G > A CR Dead(10 M)
40 56 F M2 inv(9) 15 20%/82% 30 bp del 2502-2531 CR Dead(SCT)
47 31 F M5 del(13) 1.5 95%/27% 2501 C > T N0 Dead(3 M)
48 20 F M5 normal 30.4 4.5%/71% 2501 C > T N0 Dead(3 M)
53 53 F M3 t(4;17) 7.9 82%/1.6% 55 C > T CR Alive
56 54 F M5 normal 2.19 95%/28% 2202 C > A CR Relapse(6 M)
68 52 M M5 normal 28.8 97%/42% 2644 C > T No Dead(6 M)
77 76 M M5 normal 67 No 2645 G > A Arg882His CR Dead(13 M)
89 76 M M1 normal 17.3 CD13 CD34 1906 G > A 2191 T > C NR Dead(3 M)
94 61 F M5 normal 132 CD7CD13CD33 2141C > G NO Dead(1 M)
100 46 M M5 normal 4.5 CD13CD34 1792C > T 2375 G > A NR Dead(1 M)
  1. CR Complete remission, No no chemotherapy, NR not remission, M month.