Table 3 A summary of in vitro IC ₅₀ of Flavokawain A, B, C in selected cancer cell lines

Flavokawain A

T24

~17

RT4

~17

EJ

~17

L-02

n.c.

HepG2

n.c.

Flavokawain B

KB

20.05 ± 0.4

MCF-7

49.30 ± 1.8

Ca Ski

31.10 ± 1.3

HCT116

~25

A549

~25

HFW

~25

NIH3T3

~25

MRC5

17.2 ± 0.5

T24

4.39-8.80

RT4

~18

EJ

~9-18

LAPC4

32

LNCaP

48.3

PC-3

6.20

DU145

3.90

WPMY-1

2.25

22RV1

16.6

C4-2B

2.2

L-02

35.15 ± 2.56

HepG2

62.38 ± 5.04

HSC-3

~18

Cal-27

~27

A-2058

~18

SYO

~9-18

HS-SY-II

~18-27

H460

18.2

ACC-2

4.69 ±0.43

T24

~8-17

Flavokawain C

RT4

~1.5-17

EJ

~8.33

L-02

57.04 ± 2.32

HepG2

59.48 ± 2.72