Table 2 Analysis of LAK cytotoxic activity toward H22 cells (mean ± SEM, n = 8)
From: Downregulation of the H-2Kd gene by siRNA affects the cytotoxicity of murine LAK cells
Experimental group | Effector/target cell ratio | |||
|---|---|---|---|---|
10:1 | 20:1 | 30:1 | 40:1 | |
Control | 28.6 ± 4.1 | 45.2 ± 4.8 | 68.4 ± 5.0 | 81.6 ± 5.9 |
siRNA-1 | 27.6 ± 2.1 | 40.6 ± 5.1*#▲ | 55.4 ± 4.1*#▲ | 65.0 ± 2.1*#▲ |
Mock-transfected | 26.9 ± 5.6 | 46.9 ± 5.7 | 70.3 ± 6.0 | 80.5 ± 4.6 |
Non-silencing | 30.3 ± 3.9 | 44.3 ± 3.8 | 67.0 ± 4.9 | 82.0 ± 2.6 |