Table 3 Analysis of LAK cytotoxic activity toward K562 cells (mean ± SEM, n = 8)
From: Downregulation of the H-2Kd gene by siRNA affects the cytotoxicity of murine LAK cells
Experimental group | Effector/target cell ratio | |||
|---|---|---|---|---|
10:1 | 20:1 | 30:1 | 40:1 | |
Control | 30.1 ± 9.8 | 50.1 ± 6.4 | 63.4 ± 7.6 | 76.8 ± 5.8 |
siRNA-1 | 28.4 ± 36.9*#▲ | 31.3 ± 6.5*#▲ | 36.9 ± 5.9*#▲ | 49.6 ± 7.7*#▲ |
Mock-transfected | 28.9 ± 6.7 | 49.9 ± 5.8 | 66.3 ± 8.0 | 74.9 ± 8.1 |
Non-silencing | 31.4 ± 8.7 | 51.2 ± 9.1 | 64.9 ± 8.9 | 80.0 ± 9.7 |